Treatment of Galloway Mowat Syndrome with Herbal Remedies

Abstract

Galloway Mowat syndrome is a very rare genetic disorder which results in various developmental and physical abnormalities, specifically the progressive kidney disease and certain neurological abnormalities. Developmental milestones of affected children are late and also they do not have proper hand gestures or verbal communication. There are not many people aware about it hence the diagnosis can be delayed, so let us learn about it in detail and herbal remedies which can help in management of the condition.

INTRODUCTION

It is a rare genetic disorder involving more than one system of the body which results in degeneration of the nervous system along with delay in developmental milestones, cerebellar atrophy, progressive microcephaly and cerebral atrophy. Usually the onset of disease is in the first few months of child’s life but it is diagnosed in childhood (after infancy) when the nephrotic syndrome is developed and further investigations confirms the diagnosis of Galloway Mowat syndrome.

It is a rare genetic disorder involving more than one system of the body which results in degeneration of the nervous system along with delay in developmental milestones, cerebellar atrophy, progressive microcephaly and cerebral atrophy. Usually the onset of disease is in the first few months of child’s life but it is diagnosed in childhood (after infancy) when the nephrotic syndrome is developed and further investigations confirms the diagnosis of Galloway Mowat syndrome. Physically the child bear’s head of smaller circumference than the normal to that particular age, and in some cases hiatal hernia is also present. There are neurological ailments like child possesses diminished tone of muscles, along with spasms of muscle, seizures, abnormal movements, abnormal movements of eyes, and impairment of vision. Milestones of the child are delayed that is speech, teething etc. Nephrotic syndrome is the most common cause of death of these children before attaining their teenage.

SIGNS AND SYMPTOMS

Although the major symptoms present in Galloway Mowat syndrome are established by the researchers in order to make an outline of the syndrome but still the complete pathogenesis is not known about it. Also as it is a rare disorder, it is difficult to conclude about it clearly. Every individual is different from others similarly don’t forget that all the symptoms mentioned below will not be present in every individual suffering from Galloway Mowat syndrome. However some of the major signs and symptoms observed are

• Malformation of face and head like microcephaly
• Abnormally narrow and high forehead
• Small jaw bones
• Optic atrophy due to degeneration of optic nerve
• Passing of esophagus through an abnormal opening called hiatal hernia
• Gastroesophageal reflux resulting in often vomiting in infants
• Esophagitis
• Spasm of larynx
• Nephrotic syndrome resulting proteinuria
• Ascites and edema
• Renal failure
• Epilepsy
• Seizures

CAUSES

Galloway Mowat syndrome is the genetic disorder caused due to alteration in certain genes which are responsible for the production of the protein that are important for many vital functions in the body. Due to the alteration in this gene, protein produced is absent, faulty or inefficient. Hence this faulty protein normally has some specific functions which on becoming abnormal affect the various organs and their functioning in the body.

DIAGNOSIS

Thorough clinical evaluation after the birth of the child by the doctor can help in diagnosis of Galloway Mowat syndrome. Specialized laboratory tests, striking and peculiar physical findings, and genetic testing also play a major role in establishing the diagnosis of the disease. Certain tests like MRI of the brain, and urinary analysis are done.

TREATMENT

Treatment is symptoms specific, i.e. the presenting complaints in the individual patient are treated.  In conventional systems of medicine various specialist doctors are involved for the treatment like kidney specialist to treat the nephrotic syndrome, pediatricians, gastroenterologist, surgeons, neurologist, physical therapist etc as per the symptoms.

Ayurveda can also help in management of this disease and you don’t have to run different doctors for that. As per Ayurveda a disease is caused due to the vitiation of any of the three dosha, i.e. Vata, Pitta and Kapha and making a balance in these doshas can help in eradication of the disease. Various herbs and other natural compounds are used in the form of medicine to treat the ailments naturally.

HERBAL REMEDIES GALLOWAY MOWAT SYNDROME BY PLANET AYURVEDA

Planet Ayurveda is a well known pharmaceutical company that deals with the production of herbal products and medicines which are efficiently used to treat various acute and chronic diseases naturally. No preservatives, chemicals, yeast, dye, filler, or color is used in the production of the products in Planet Ayurveda. This is the reason its products are being used by millions of people throughout the world. All the herbal remedies are produced under the strict supervision of MD Ayurveda doctors as per the classical Ayurvedic literature. For Galloway Mowat syndrome Planet Ayurveda offers a combination of herbal remedies to manage the condition naturally.

Product List

1. Punarnava mandur
2. Reno Plan syrup
3. Kumar kalyan ras
4. Neuro Plan syrup
5. Digesto Plan syrup

Product Description

1. Punarnava Mandur

These herbal tablets work amazingly to treat various ailments in the body. Punarnava mandur is formulated using Punarnava (Boerhavia diffusa), Maricha (Piper nigrum), Chavya (Piper Chaba), Haritaki (Terminalia chebula), Amalaki (Emblica officinalis), Chitrak mool (Plumbago zeylanica), Vidanga (Embelia ribes), etc. It clears the toxins from the body and balances the tridosha.

These herbal tablets work amazingly to treat various ailments in the body. Punarnava mandur is formulated using Punarnava (Boerhavia diffusa), Maricha (Piper nigrum), Chavya (Piper Chaba), Haritaki (Terminalia chebula), Amalaki (Emblica officinalis), Chitrak mool (Plumbago zeylanica), Vidanga (Embelia ribes), etc. It clears the toxins from the body and balances the tridosha.

2. Reno Plan Syrup

This purely herbal syrup helps in treating the kidney ailments like albuminuria, proteinuria etc. Reno Plan syrup helps in restoring the function of the kidneys. It is prepared from herbs like Punarnava (Boerhavia diffusa), Trapush (Cucumis sativus), Gokshura (Tribulus terrestris), Bhumi amla (Phyllanthus niruri), Kaasni (Cichorium intybus) etc.

Dosage– Take 1 teaspoon twice daily after meals with plain water

3. Kumar Kalyan Ras

It is a herbo-mineral formulation that is formulated using Kumari rasa (Aloe vera’s juice extract), Mukta bhasma (Calx of pearl), Shuddha Parada (Purified mercury), Loha bhasma (Calx of iron) etc.

Dosage– Take 1 tablet daily after meals with plain water

4. Neuro Plan Syrup

Neuro Plan syrup is formulated from neuroprotective herbs like Brahmi (Bacopa monnieri), Shankhpushpi (Convolvulus pluricaulis), Mandukaparni (Centella asiatica), Ashwagandha (Withania somnifera) etc. This syrup helps in fighting all kinds of nervous system related diseases and its associated symptoms.

Dosage- Take 1 teaspoon twice daily after meals with plain water

5. Digesto Plan Syrup

Herbs like Amalaki (Emblica officinalis), Ajwain (Trachyspermum ammi), Haritaki (Terminalia chebula), Bibhitaki (Terminalia bellerica), Marich (Piper nigrum) etc are used in this syrup. Digesto Plan syrup helps to maintain healthy digestion and treats ailments related to it.

Dosage– Take 1 teaspoon twice daily after meals with plain water

Note

If the child is too young or infancy so that he/she cannot take tablets as a whole, crush the tablets, mix it in the syrups given and give it to the child.

CONCLUSION

Galloway Mowat syndrome is a genetic disorder hence it won’t be easy to treat or manage it. However, proper Ayurvedic treatment can help to manage it naturally. Also as these herbal remedies are free from all types of chemicals, no more harm is caused to the child’s body.