How Chaple’s Syndrome can be Managed Naturally?

Abstract

Chapel syndrome is a rare disorder. It is an autoimmune disease in which the body starts attacking its own cells leading to red blood cells destruction. As it is a rare genetic disorder, it can be managed by Herbal formulations.

Introduction

Chapel syndrome is known as CD55 deficiency also called DAF deficiency. It is a rare and potential fatal autoimmune disease. Complement decay or decay accelerating factor(DAF) is a membrane protein. In humans it is encoded by the CD55 gene. DAF is present on the surface of all blood cells, endothelial cells and various other tissue cells. Its main role is to prevent the cells from autologous complement attack by preventing the formation of C3 And C5 convertases. DAF deficiency is linked to various types of diseases such as paroxysmal nocturnal haemoglobinuria and other autoimmune diseases. Chapel syndrome is a form of PIL(Primary intestinal lymphangiectasia) or Waldmann’s disease. In Chaple syndrome there are a range of symptoms including pain in abdomen, vomiting and bloody diarrhea.

Causes

Chapel syndrome is a rare genetic disorder which is caused by loss of complementary protein. There is loss of DAF(decay accelerating factor) or CD55. DAF(Decay accelerating factor) plays an important role in maintaining the immune system. It regulates the immune system through complement dependent and independent regulation of innate and adaptive immunity. The major function of DAF is to protect host cells from complement mediated attack. It inhibits the process of C3 and C5  by blocking the formation of C3 and C5 converters and initiating their decay. In the absence of CD55 , the complement system starts attacking red blood cells and causes their destruction. It is an autosomal recessive inherited disorder that means two copies of an abnormal gene must be present in order for the disease to get manifested.

Symptoms of Chaple Syndrome

Chapel syndrome is characterized by hyperactivity of a complementary system. It is characterized by paroxysmal autoimmune haemolysis (Destruction of red blood cells by complement system) and protein losing enteropathy( It is a condition of gastrointestinal tract which is characterized by loss of proteins from the body due to drainage of gut).

Chaple syndrome’s symptoms include:

• Red color of urine
• Abdominal pain
• Difficulty in swallowing
• Bloody diarrhea
• Fever
• Swelling in legs
• Frequent lung infections
• Deep vein thrombosis in severe conditions
• Erectile dysfunction in men

Diagnosis

The diagnosis of Chaple syndrome is done on the basis of Flow cytometry. Flow cytometry is an immunophenotyping technique which is used to analyze the expressions of cell surface.

Ayurvedic Aspect of Chaple Syndrome

As per Ayurveda Genetic disorders are considered under beej dosha. According to Ayurveda there are three genetic units in the form of beej(Germinal cells), Beejbhag(Chromosomes) and beejbhagavyava( Gene). According to Acharya Charak teratogenic depends upon the condition of beej. If beej is defective, the body developing from it will be considered abnormal. The goal of Ayurveda is to prevent such diseases. Ayurveda has explained six procreative factors which play an important role in development of genetic factors.

Herbal Remedies By Planet Ayurveda

Planet Ayurveda is offering an effective combination for Chaple syndrome. It includes a combination of herbs which enhances our immunity. This herbal formulation also prevents occurence of such diseases.

It includes:

1. Ashwagandha capsules – 2 capsules twice daily
2. Punarnava mandoor – 2 tablets twice daily
3. Immune booster -1cap twice daily
4. Wheatgrass powder – 1 teaspoon mixed in a glass of water twice a day
5. Pitta balance-1 capsule twice daily
6. Swarna vasant malti ras- 1 tab twice daily

1. Ashwagandha Capsules

Ashwagandha capsules are prepared by pure extract of Ashwagandha( Withania somnifera). This herb is highly beneficial in treating general debility, stress, anxiety. Basically it strengthens our body and acts as a nerve tonic. Ashwagandha helps in soothing and calming the mind.

2. Punarnava mandoor 

Punarnava mandoor is in the form of tablets and it is a combination of multiple herbs. It is prepared by extract of following herbs:

• Punarnava (Boerhavia diffusa)
• Shunthi(Zingiber officinale)
• Pippali(Piper longum)
• Maricha(Piper nigrum)
• Amalaki (Emblica officinalis)
• Haritaki (Terminalia chebula)
• Chavya (Piper chaba)
• Haridra (Curcuma longa)
• Vidanga(Embelia ribes)
• Chitrak mool(Plumbago zeylanica)
• Mandoor bhasma( Ferric oxide calx)

Punarnava is the main ingredient of punarnava mandoor. It has anti-inflammatory and antifibrinolytic properties. It is highly useful in management of edema, anemia, jaundice and internal inflammation. These multiple herbs on combination help in increasing blood count, improve blood quality and help in removal of toxins from blood.

3. Immune Booster

Immune booster is an effective product to boost immunity power. This herbal formulation is a combination of grape seeds( Vitis vinifera), bhumi amla( Phyllanthus niruri), and cow colostrums( Bovine colostrums). Immune booster is very useful in almost all ailments. It helps in detoxification of the body and provides resistance to the body to fight against various diseases.

4. Wheatgrass powder 

Wheatgrass powder is a 100% Ayurvedic product that is prepared by dried powder of ground parts of young wheat(Triticum aestivum). It helps to increase immunity power and promotes healthy digestion.

5. Pitta balance

Pitta balance as its name suggests to balance vitiated pitta dosha in the body. It’s ingredients are praval pishti(Coral calcium), Akik pishti(An Ayurvedic calcium compound), Kamdudha ras( Calcium compound),Mukta pishti( pearl calcium) and giloy( Tinospora cordifolia). It is rich in calcium hence it provides strength to bones. It is best for the digestive system.

6. Suvarna Vasant Malti Ras

It is a dietary supplement which contain Suvarna bhasma( Gold Calcined), Mukta bhasam( Pearl calcined), Shudh hingul( Cinnabar) and maricha (Piper nigrum). It is best used for general debility. It also improves immunity.

Conclusion

Hence it is concluded from the above discussion that Chaple syndrome is a rare genetic disorder which occurs due to CD55 deficiency. It is an autoimmune disease and it can be managed by herbal formulations which helps in boosting immunity power.