Herbal Remedies For Waldenstrom Macroglobulinemia – Causes & More

Introduction

Waldenstrom macroglobulinemia is a rare type of malignant blood cell cancer that begins by excess production of abnormal white blood cells in the bone marrow that crowd out healthy blood cells. This disease is a kind of non-Hodgkin’s lymphoma, which starts in white blood cells called Lymphocytes, it is a part of our immune system that acts as a defence barrier against microorganisms. Some of the lymphocytes are called B cells, and act as the body’s defence power. In this disease this process disturbs and the B cells turn into cancer cells, which means they grow out of control. Waldenstrom macroglobulinemia is characterised by the presence of elevated serum viscosity, high level of macroglobulin (immunoglobulin M [IgM] and the presence of a lymphoplasmacytic infiltrate in the bone marrow. Due to these factors blood becomes thicker than normal and makes it harder to move through blood vessels. Waldenstrom macroglobulinemia is a disease that occurs more frequently in older males because of its indolent nature, many patients are able to live actively and with treatment patients may experience many years of symptom-free remission.

Causes

• Experts say that changes in DNA may lead to Waldenstrom macroglobulinemia. Most of the time, these affected cells have changes on genes called MYD88 and on CXCR4. The DNA changes may cause the genes to get stuck in the ‘on’ position, so cells live longer than normal. These changes mostly happen in later stages of life so most affected patients are of 50 or older people.
• The disease is more common in men than women.
• If someone already has a condition called MGUS (monoclonal gammopathy of undetermined significance) more reliable to get Waldenstrom macroglobulinemia.
• White people are more likely to be effective than other races.
• Genetic Factor: If any family member has already been diagnosed with Waldenstrom macroglobulinemia or any other type of B-cell lymphoma, then patients also have a highly increased risk of developing the disease.
• Environmental Factors: Exposure to farming, wood dust, pesticides, and organic solvents.

Pathophysiology

Waldenstrom macroglobulinemia is a type of malignant cancer affecting two types of cells that are plasma cells and lymphoplasmacytoid cells. These both are WBCs. It is characterised by the presence of elevated serum viscosity, circulating antibodies, high level of macroglobulin (immunoglobulin M [IgM] and the presence of a lymphoplasmacytic infiltrate in the bone marrow which is made and secreted by the cells involved in the disease.

Waldenstrom macroglobulinemia grows and spreads slowly and is a type of lymphoproliferative disease which has similar clinical characteristics with the indolent non-Hodgkin lymphomas.

Sign And Symptoms

Waldenstrom macroglobulinemia usually begins in later stages of life and is a slow growing indolent cancer. Firstly appearing symptoms in these patients are weakness and extreme fatigue caused due to shortage of red blood cells. Increased level of IgM can thicken the blood viscosity and impairs the circulation leads to Hyperviscosity Syndrome. Patients show signs of anaemia, easy bruising, bleeding from nose and gums. Other symptoms are headache, fevers, night sweats, lack of appetite and weight loss without trying, frequent infections or allergies, breathlessness, changes in vision, numbness or tingling sensation in hands and feet, confusion, dizziness, clumsiness, peripheral neuropathies, enlargement of lymph nodes, hepatomegaly, splenomegaly, and rarely stroke or coma.

Increased level of IgM can thicken the blood viscosity and impairs the circulation leads to hyperviscosity syndrome.

Diagnosis

• Bone marrow biopsy
• Blood tests to show the level of IgM and presence of protein
• CT scan
• ESR levels

Allopathic Treatment

• Symptomatic medications
• Corticosteroids

Ayurvedic View Of Waldenstrom Macroglobulinemia

Now we are going to discuss the ayurveda aspect of Waldenstrom macroglobulinemia. As per ayurveda we can correlate the above condition with 𝘙𝘢𝘬𝘵𝘢 𝘷𝘢𝘩𝘢 𝘴𝘳𝘰𝘵𝘢𝘴 𝘥𝘶𝘴𝘩𝘵𝘪. 𝘚𝘳𝘰𝘵𝘢𝘴 are the channels from which sravana and flow of the body substances takes place. Rakta vaha srotas are those channels that are involved in blood circulation. 𝘠𝘢𝘬𝘳𝘪𝘵𝘢 (Liver) and 𝘱𝘭𝘦𝘦𝘩𝘢 (Spleen) are the mulas or roots of Rakta vaha srotas. Causes of Rakta vaha srotas dushti are –

• Vidahi anna (food that cause burning sensation)
• Snigdh anna (oily food)
• Ushna anna (excessive hot food)
• Drava anna (liquid diet)
• Atyadhik atapa sevan (exposure to sunlight)
• Atyadhik anala sevan (exposure to fire)

Symptoms of Rakta Vaha Srotas Dushti Are

• Rakta alpata (anaemia)
• Twak rukshta (dryness of skin)
• Twak sfutana (cracking of skin)
• Shonit aagmana (bleeding from different parts)
• Rakta netrata (reddish eyes)
• Aasya paak (stomatitis)
• Vidradhi (abscess)
• Shvitra (leukoderma)
• Pama (scabies)
• Kotha (scabies)

Treatment of Rakta Vaha Srotas Dushti Are

• Raktapitta hara kriya (management of bleeding disorders)
• Virechana karma (medicated purgation)
• Upavasam (fasting)
• Raktamokshana kriya (bloodletting treatment)

For Rakta vaha srotas dushti and the management of Waldenstrom macroglobulinemia Planet Ayurveda provides you with a variety of herbal medicines that we will discuss now.

Herbal Remedies For Waldenstrom Macroglobulinemia By Planet Ayurveda

Planet Ayurveda is a herbal manufacturing company that provides great treatment with miraculous results for every health concerned patient. Here , formulations are made under proper guidance by MD Ayurveda Doctors and these medications are 100% natural. There are no adhesives, dyes, fillers, or adulterants used. There are no side effects of our formulations that are most effective herbal and natural. In the above condition Planet Ayurveda gives many formulations to manage the disease very well. These are-

• Boswellia Curcumin
• Graviola
• Mahamanjisthaghan Vati
• Pitta Balance
• Tumotrim Capsules
• Telo-extension
• Navkarshik Churna
• Vikramprash

Herbal Remedies For Waldenstrom Macroglobulinemia

Product Description:-

1. Boswellia Curcumin

Is a polyherbal capsule. Consists of Shallaki 𝘉𝘰𝘴𝘸𝘦𝘭𝘭𝘪𝘢 𝘴𝘦𝘳𝘳𝘢𝘵𝘢 and Curcumin (Haridra) Curcuma longa. This has various benefits like it is rich in carbohydrates, reduces pain, also has anti-inflammatory properties, and may prevent loss of cartilage.. It also helps to improve appetite and has anti-allergic, antiseptic and blood cleansing properties. From an ayurvedic perspective, this acts as rasayana and balances all doshas.

Dosage- 1 capsule twice daily with plane water after meals.

2. Graviola

Is a single herbal capsule. Consists of Graviola 𝘈𝘯𝘯𝘰𝘯𝘢 𝘮𝘶𝘳𝘪𝘤𝘢𝘵𝘢. It has various benefits in body functions. It acts as antioxidant, anti-inflammatory properties that may relieve pain. Graviola extract is very useful against Breast cancer, pancreatic cancer and also helps to kill cancer cells all over the body.

Dosage- 1-2 Capsules once or twice daily with plain water after meals.

3. Mahamanjisthaghan Vati

It is a poly herbal tablet. Consists of Manjistha 𝘙𝘶𝘣𝘪𝘢 𝘊𝘰𝘳𝘥𝘪𝘧𝘰𝘭𝘪𝘢, Mustaka 𝘊𝘺𝘱𝘦𝘳𝘶𝘴 𝘳𝘰𝘵𝘶𝘯𝘥𝘶𝘴, Giloy 𝘛𝘪𝘯𝘰𝘴𝘱𝘰𝘳𝘢 𝘤𝘰𝘳𝘥𝘪𝘧𝘰𝘭𝘪𝘢, Shunthi 𝘡𝘪𝘯𝘨𝘪𝘣𝘦𝘳 𝘰𝘧𝘧𝘪𝘤𝘪𝘯𝘢𝘭𝘪𝘴, Kushtha 𝘚𝘢𝘴𝘴𝘶𝘳𝘦𝘢 𝘭𝘢𝘱𝘱𝘢, Haridra 𝘊𝘶𝘳𝘤𝘶𝘮𝘢 𝘭𝘰𝘯𝘨𝘢. This formulation helps to balance tridoshas but specially pacifies excessive pitta, and supports healthy blood circulation all over the body. It has cell rejuvenation properties. This useful formulation can be used as diuretic, demulcent and has great immunomodulatory properties that can hamper tumorous growths and enhance anticancer activities.

Dosage- 2 tablets twice daily with plain water after meals.

4. Pitta Balance

It is a poly herbal capsule. Consists of Praval pishti (coral calcium), Akik pishti (agatte calcium), Jawar mohra pishti (an ayurvedic calcium compound), Mukta pishti (pearl Calcium), Giloy satva (𝘛𝘪𝘯𝘰𝘴𝘱𝘰𝘳𝘢 𝘤𝘰𝘳𝘥𝘪𝘧𝘰𝘭𝘪𝘢 stem 𝘦𝘹𝘵𝘳𝘢𝘤𝘵). This is an incredible ayurvedic formulation that has anti inflammatory, digestive, anti microbial, analgesic and has great immunomodulatory properties that can treat general debility, peripheral neuropathies, restlessness. It pacifies all the three doshas and has a positive effect on various dhatus which are rasa, rakta, mamsa, asthi, shukra.x

Dosage- 1-2 capsules twice daily, with plain water, after meals.

5. Tumotrim Capsules

It is a polyherbal capsule. Consists of Haridra 𝘊𝘶𝘳𝘤𝘶𝘮𝘢 𝘭𝘰𝘯𝘨𝘢, Shallaki 𝘉𝘰𝘴𝘸𝘦𝘭𝘭𝘪𝘢 𝘴𝘦𝘳𝘳𝘢𝘵𝘢, Tulsi 𝘖𝘤𝘪𝘮𝘶𝘮 𝘚𝘢𝘯𝘤𝘵𝘶𝘮, Ashwagandha 𝘞𝘪𝘵𝘩𝘢𝘯𝘪𝘢 𝘴𝘰𝘮𝘯𝘪𝘧𝘦𝘳𝘢, Maricha 𝘗𝘪𝘱𝘦𝘳 𝘯𝘪𝘨𝘳𝘶𝘮, Shunthi 𝘡𝘪𝘯𝘨𝘪𝘣𝘦𝘳 𝘰𝘧𝘧𝘪𝘤𝘪𝘯𝘢𝘭𝘪𝘴. This is an incredible ayurvedic formulation that reduces pain, also has anti-inflammatory properties, and a great detoxifier. It also helps to improve appetite and has anti-allergic, antiseptic and blood cleansing properties. It pacifies all the three doshas by its various components.

Dosage- 1-2 capsules twice daily, with plain water, after meals.

6. Telo-extension

It is a poly herbal formulation in a capsule. Ingredients are Ashwagandha 𝘞𝘪𝘵𝘩𝘢𝘯𝘪𝘢 𝘴𝘰𝘮𝘯𝘪𝘧𝘦𝘳𝘢 , Grape seed 𝘝𝘪𝘵𝘪𝘴 𝘷𝘪𝘯𝘪𝘧𝘦𝘳𝘢 , Amalaki 𝘌𝘮𝘣𝘭𝘪𝘤𝘢 𝘰𝘧𝘧𝘪𝘤𝘪𝘯𝘢𝘭𝘪𝘴 etc. this assista in normal functioning of the body. These all herbs have the best rasayana properties and can be used daily for a healthy body and mind. These drugs have great properties of tridosha shamana and regulate body functions.

Dosage- 1-2 capsules once or twice daily, with plain water, after meals.

7. Navkarshik Churna

This is a poly herbal churna. Consists of Amalaki 𝘌𝘮𝘣𝘭𝘪𝘤𝘢 𝘰𝘧𝘧𝘪𝘤𝘪𝘯𝘢𝘭𝘪𝘴, Haritaki 𝘛𝘦𝘳𝘮𝘪𝘯𝘢𝘭𝘪𝘢 𝘤𝘩𝘦𝘣𝘶𝘭𝘢, Bahera 𝘛𝘦𝘳𝘮𝘪𝘯𝘢𝘭𝘪𝘢 𝘣𝘦𝘭𝘭𝘦𝘳𝘪𝘤𝘢, Vacha 𝘈𝘤𝘰𝘳𝘶𝘴 𝘤𝘢𝘭𝘢𝘮𝘶𝘴, Neem 𝘈𝘻𝘢𝘥𝘪𝘳𝘢𝘤𝘩𝘵𝘢 𝘪𝘯𝘥𝘪𝘤𝘢 etc. Beneficial in eye disorders, for good digestion, detoxification ,various inflammatory conditions and purification of blood .

Dosage- 1 teaspoon twice daily, with plain water, after meals.

8. Vikramprash

This formulation is in the form of avaleha. Consists of Bilva 𝘈𝘦𝘨𝘭𝘦 𝘮𝘢𝘳𝘮𝘦𝘭𝘰𝘴, Agnimantha 𝘗𝘳𝘦𝘮𝘯𝘢 𝘮𝘶𝘤𝘳𝘰𝘯𝘢𝘵𝘢, shyonak 𝘖𝘳𝘰𝘹𝘺𝘭𝘶𝘮 𝘪𝘯𝘥𝘪𝘤𝘶𝘮, kashmarya 𝘎𝘮𝘦𝘭𝘪𝘯𝘢 𝘢𝘳𝘣𝘰𝘳𝘦𝘢 etc. Maintains balance of the doshas, dhatus, and the malas. This formulation acts as an antioxidant that boosts immunity by killing various infected micro organisms, may reduce cancer risk in individuals, is a natural detoxifying agent and has anti-inflammatory properties.

Dosage- 1-2 teaspoons twice daily, with plain water, after meals.

Conclusion

Waldenstrom macroglobulinemia is a rare type of malignant blood cell cancer that begins by excess production of abnormal white blood cells in the bone marrow. This disease is more common in older men than women. It is a type of malignant cancer affecting two types of cells that are plasma cells and lymphoplasmacytoid cells. Most common symptoms are weakness, extreme tiredness, fever, night sweats and weight loss etc. As per ayurveda aspect it may be correlated with Rakta vaha sroto dushti and treated as raktapitta har kriya , virechana karma. Medication can improve patients’ health and increase their longevity. In case of any queries you can contact www.planetayurveda.com