Ayurvedic Remedies for Hereditary Motor Sensory Neuropathy

Abstract

Hereditary motor sensory neuropathy is an inherited and progressive disease of the nerves. It is an illness of the nervous system, especially the peripheral nervous system. It is a group of neurodegenerative diseases associated with weakness and numbness. The deprived status of limbs can be noticed due to poor nerve conduction. It is evident in studies that approx 20 genes are associated with HMSN. Hence studies are associated with the understanding of peripheral nerves and molecular diagnostics may enhance the knowledge and make a change.   In this article, we are going to discuss HMSN (Hereditary Motor sensory neuropathy) and its ayurvedic treatment.

Introduction

HMSN is an inherited disease known to be progressive in nature. It is also called Charcot-Marie-tooth disease. It is progressive in nature and associated with weakness in the body and nerve numbness as well. HMSN is associated with degeneration of neural tissues and associated with abnormal functioning of limbs. The hypertrophic condition mainly causes neural stiffness and starts the demyelination of nerves. It can be congenital or developmental in nature.

Types

1. Types 1A and 1B (Dominantly inherited hypertrophic demyelinating neuropathies)
2. HMSN type 2 (Dominantly inherited neuronal neuropathies)
3. HMSN type 3 (Neuropathy of infancy [Dejerine-Sottas])
4. Neuropathy [Associated with phytanic acid excess)

Symptoms – Symptoms of HMSN are

Common signs and symptoms of HMSN

1. Weakness in the muscles, feet, ankle, and legs.
2. Hammer’s toes
3. Flat foot
4. Difficulty in lifting the foot.
5. Lack of sensation in the limbs
6. Due to poor blood circulation, hands and feet are cold.
7. Muscle loss.
8. The champagne shape of the leg
9. Tremors
10.  Abnormal lateral curvature of the spine.
11. Difficulty while eating, speaking, breathing
12. Associated pain

Causes

HMSN (Hereditary motor sensory neuropathy) is caused by a mutation in the genes (especially chromosomes 17 and 1) which leads to the damage of the peripheral nerves. Inheritance of disease can be due to autosomal dominant or autosomal recessive manner.

Diagnosis

The following diagnostic methods are

1. Nerve conduction test.
2. Electromyography (EMG).
3. Genetic testing.
4. Nerve Biopsy.

Ayurvedic concept of HMSN

Ayurvedic concept of diseases is based on the Vitiation of three doshas – Vata, Pitta, and Kapha. The health of an individual is based on the good balance of these three doshas. Vitiation of any of the dosha leads to impaired health. According to the Ayurvedic point of view for HMSN whenever the Vata dosha is vitiated in the body the problems associated with nerve or degeneration of nerve or nerve conduction can be seen.

The poor lifestyle, poor diet, and ama dosha (toxins due to poor eating habits) are the leading cause of dosha vitiation. According to the classics, when Vata is vitiated in the body, it afflicts it with various disorders and thereby affects strength, complexion, happiness, and lifespan. It agitates the mind, affects all the sense organs, and causes deformities. So for the management of HMSN, it is important to realize the importance of Vata balancing and to protect its further vitiation.

Herbal Remedies

For Hereditary motor sensory neuropathy by Planet Ayurveda- Planet Ayurveda is a recognized and GMP-certified hub for the manufacturing of the best and result-oriented ayurvedic formulations. Formulations are based on the Principles of classical ayurvedic texts and healing the problems of mankind. The prime goal of Planet Ayurveda is to promote health-related awareness among the masses and guide them about ayurvedic solutions for a healthy life.  Following are the herbal formulations/remedies to manage the HMSN condition.

1. Ashwagandha Ghan Vati
2. Atirasadi Churna
3. Kumari Saar
4. Tribulus Power
5. Musli Strength
6. Vrihat Vatchintamani Ras
7. Neurogenie capsule

Product Description

1. Ashwagandha Ghan Vati

Ashwagandha ghan vati is a classical Ayurvedic formulation. It is loaded with a pure extract of Ashwagandha (Withania somnifera). Ashwagandha is loaded with withanine, pseudo withanine, and sominiferine-like compounds. Withanine is sedative in action and acts as a natural stress reliever and it is useful to enhance sexual vigor, penile dysfunction, conditions like fatigue, palpitation, aging, and bradycardia as well as prolonged hypotension. It acts as the best nervine tonic, strengthens your muscles, and maintains proper nourishment of the healthy tissues of bones and muscles. Due to all the properties, it is helpful in conditions like HMSN.

Dosages:- 2 twice daily with lukewarm water after meals.

2. Atirasadi Churna

Atirasadi churna is a blend of miraculous herbs. The chief ingredients of this herbal formulation are Safed Musli(Chlorophytum borivilianum), Shalmali (Salmalia malabarica) Shatavari(Asparagus racemosus), Vidari kand (Pueraria tuberosa),  Kali musli (Curculigo orchioides), Ashwagandha (Withania somnifera), Safed Behmen (Centaurea Behen ), Taalmakhana (Hygrophilla Spinosa) and other effective herbs. Atirasadi churna is able to enhance immunity and nerve conduction.

Dosages:- 1 tsp twice daily with warm milk

3. Kumari Saar

Kumari Saar is a pure extract of Ghrit kumari (aloe vera). Aloe vera is loaded with a variety of essential nutrients. Aloe vera is purgative in action with anti-inflammatory and antimicrobial properties. Aloe vera can be beneficial in constipation, and various disorders like eczema, ulcers, psoriasis, acne, bites, and burns. A molecule named Acemannan which is there in aloe vera gel stimulates macrophages and releases immune system potentiators, it enhances T cells functions and production of interferon, thus acting as an immunity booster.

The presence of salicylate and carboxypeptidase in aloe gel help to inhibit the pain-producing agent i.e Bradyk and hence help to reduce the pain associated with neuropathic conditions. As we have discussed aloe vera helps to heal burns, it is because it inhibits thromboxane synthesis hence promoting burn healing. Aloe vera works efficiently on damaged skin, bronchial tubes, and genital tracts. Aloe vera has antimicrobial and anti-inflammatory properties. Thus it is efficient in HMSN conditions.

Dosage:- 2 tsp twice daily after meals.

4. Tribulus Power

Tribulus power is a well-known herbal formulation that is loaded with standardized extracts of Gokshura (Tribulus Terrestris) herbs. Tribulus is a well-known herb that acts as a tonic in sexual inefficiency in males. On the basis of properties, it is diuretic, muscle relaxant, and spasmolytic in nature. It is a well-known herb to increase the male sex hormone. This herb is well known for its medicinal benefits in reducing cholesterol levels, triglyceride levels, high blood pressure, serum glucose levels, and removing excessive harmful toxins from the body. It helps to enhance testosterone levels. Regular use of this formulation improves blood circulation in the tissue of the penis adding to its erectile strength. It also gives very good results in HMSN.

Dosage:- 1 cap twice daily after meal with lukewarm water.

5. Musli Strength

Musli strength is a herbal formulation of Planet Ayurveda for nervous-related disorders and muscle enhancement. The chief ingredients of Musli strength are Safed Musli (Chlorophytum borivilianum) and Gokshura (Tribulus Terrestris). Musli strength is beneficial to various kinds of neurodegenerative diseases associated with nerve degeneration.

Musli is also beneficial for eright gain and male sexual health. This herbal formulation is helpful for the improvement of nerve and bone health. The following benefits of this herbal formulation are improved stamina, confidence, fertility, sexual performance, and prevention of sexual disorders. It also boosts your immunity, gives strength to the body muscles, and gives excellent results in HMSN.

Dosage:– 1 cap twice daily with lukewarm water.

6. Vrihat Vatchintamani Ras

Vrihat Vatchintamani Ras is a classical polyherbal formulation by planet Ayurveda. The chief ingredients of this herbal formulation are Swaran Bhasma (Calx of Gold), Loha Bhasma (Calx of Iron), Mukta Bhasma (Calx of Pearl), and Abhrak Bhasma (Calx of Mica), Rajat Bhasma (Calx of Silver) and many more. It is beneficial to maintain the healthy functioning of the body. It also helps to balance the Aggravated Vata dosha in our body. It is beneficial to relax the muscles of the body and gives relief from the stiff joints. It gives the best results in HMSN.

Dosage:- 1 tablet twice to be chewed

7. Neurogenie capsule

Neurogenie cap is a polyherbal capsule formulated by Planet Ayurveda. It is prepared from herbs like Brahmi (Bacopa monnieri), and Ashwagandha (Withania somnifera). As we all know Brahmi is a Vata Kapha nashak herb due to its hot and pungent properties. These herbs act as a nervine tonic, and immunity booster, and are rich in antioxidants. These herbs are beneficial for reducing stress and pacifying anxiety.

Dosage:- 1 cap twice daily with lukewarm water.