Peripheral Neuropathy Types and Treatments In Ayurveda

Abstract

Peripheral neuropathy is a typical entanglement of large numbers of the systemic amyloidosis. Albeit the reason for neuropathy isn’t properly clear, it is possibly connected with amyloid deposition inside the nerve. This might prompt central, multifocal, or diffuse neuropathies including sensory, motor as well as autonomic filaments. The features or symptoms rely upon the distribution of the affected nerves. One of the most well-known aggregates is sensorimotor polyneuropathy, which is characterised by numbness, extreme weakness and neuropathic pain. In this article we shall discuss amyloid polyneuropathy disease in detail and discuss its management in the contemporary system of medicine and in the traditional Indian system of ayurvedic medicine. Let’s get started!!

Introduction

Amyloidoses are a group of disorders that have a diverse range of clinical manifestations. Amyloidosis is characterised by the deposition of misassembled, insoluble proteins that can ultimately result in hampering normal structure and functioning of the tissues. Till now 30 proteins have been identified as main amyloid fibril components. Based on aetiology, the deposition of amyloid can affect various organs particularly heart, liver and kidney. This deposition of amyloid can also affect the peripheral motor, sensory and autonomic nerves. Sometimes, neuropathy is the initial manifestation of the disease. Lets see further the causes, types and management of amyloidosis that affect the nervous system.

Causes of Amyloid Polyneuropathy Disease

The major cause of amyloid polyneuropathy disease is gene mutation in the TTR gene. There is an inherited fault in synthesis of enzyme transthyretin (TTR). This protein is responsible for transport of vitamin A and thyroxine hormone in the bloodstream. This leads to deposition of abnormal protein amyloid in the bloodstream and invades into the nerves which further causes neuropathy.

Risk Factors

• Age: ages between 60 and 70 are more to develop amyloidosis
• Sex: more common in men than women
• Other diseases: inflammatory conditions and chronic infections
• Family history: some types of amyloidosis are hereditary
• Kidney dialysis: abnormal proteins sometimes build up in the bloodstream and can get deposited in the tissues.
• Race: African people appear to be at higher risk of carrying a genetic mutation linked to a type of amyloidosis that can damage the heart.

Signs and Symptoms

• Severe fatigue and weakness
• Pain, tingling or numbness in the feet or hands
• Diarrhoea or constipation
• An enlarged tongue with serrations
• Skin changes such as thickening of the skin and easy bruising and purplish colored patches around the eyes.
• Swelling of the legs and ankles.
• Shortness of breath

Amyloidosis is a common term that includes all kinds of amyloid deposition sites. The presentation of amyloidosis depends on the site involved. Usually heart and kidney are commonly involved. As these are important organs. Let’s have a glimpse over it as well.

Kidney:

Deposition of amyloid in the mesangial regions and glomerular capillaries affects the filtration. This leads to high excretion of protein in the urine and nephrotic syndrome. Several types of amyloidosis are linked with nephrotic syndrome.

Heart:

Deposition of amyloid in the heart may lead to systolic and diastolic heart failure. ECG may show atrioventricular block or sinus node dysfunction.

Cardiac amyloidosis can show the features of heart failure including fatigue, edema and shortness of breath. Amyloid deposition restricts the pumping of the heart that can lead to worsening of the heart functioning and deteriorates the quality of life.

Nervous System:

Usually people with amyloidosis can develop autonomic and sensory neuropathies. Sensory neuropathy develops in a symmetrical pattern and progresses in a distal to proximal manner. Autonomic neuropathy may manifest as gastrointestinal symptoms such as early satiety, nausea, constipation. Numbness, unusual sensations and pain are the most common features of involvement of the nervous system.

Investigations

• Laboratory tests
• History
• Biopsies
• Nerve conduction studies
• Echocardiogram
• Magnetic resonance imaging (MRI)
• Nuclear imaging

Management of Amyloid Polyneuropathy Disease

Medications

• Chemotherapy
• Heart medications such as blood thinners.
• Targeted therapies
• Antidepressants
• Anti-seizure medications
• Analgesics

Surgical and other procedures

• Autologous blood stem cell transplant
• Dialysis
• Organ transplant

Ayurvedic Aspect and Management of Amyloid Polyneuropathy Disease

Ayurveda is a traditional medicinal system of India. Ayurveda has been serving mankind and the termination of the disease from their root cause. Amyloid polyneuropathy disease is a disease that occurs due to deposition of amyloid in the nerves. This can result in various symptoms according to the affected nerves.

As the vata dosha is responsible for all the neurological functions, any kind of vata vitiation leads to the symptoms such as pain, numbness, paresthesia, tingling sensation, increased or decreased movements. Further the deposition of amyloid in the nerves can be well compared with the concept of ama formation and kapha dosha aggravation. Further as it has inherited in origin, thus we can see this as beej dushti in the lens of Ayurveda.

So now the management depends on the pacification of the vitiated dosha and providing strength to the nerves and muscles and ama pachan. And we have magnificent herbs and herbal medicines that correct the disease so well.

Herbs such as amalaki (Embellica officinalis), haritaki (Terminlia chebula), bibhitaki (Terminalia bellerica), giloy (Tinospora cordifolia), bala (Sida cordifolia), erand (Ricinus communis), ashwagandha (Withania somnifera), guggulu (Commiphora mukul), draksha (Vitis vinifera), brahmi (Bacopa monnieri), yashtimadhu (Glycyrrhiza glabra) etc are beneficial in amyloid polyneuropathy disease.

Arogya vardhini vati, brahmi vati, brahma rasayana, giloy ghan vati, triphala guggul, agastya haritaki, amritprash, brahmi ghrita, shatavari ghrita, erand paka, amritadi guggulu etc are some of the classical formulations that are helpful in amyloid polyneuropathy disease.

Herbal Remedies for Amyloid Polyneuropathy Disease by Planet Ayurveda

Planet Ayurveda is an emerging US-FDA registered and ISO 9001:2015 certified Ayurvedic Company, which adhered to the aim of manufacturing standard Ayurvedic medicines as given in the various ancient scriptures of Ayurveda. Medicines are prepared without preservatives and additives and other kinds of synthesised material which cause many ill effects on the human body. Products manufactured at Planet Ayurveda are pure and devoid of any adulteration. Planet Ayurveda extends its herbal formulations that are helpful in managing amyloid polyneuropathy disease.

Given Below Are Some of the Products That Are Beneficial in Amyloid Polyneuropathy Disease

Products List

1. Boswellia Curcumin
2. Neurogenie Capsules
3. Ekangvir Rasa
4. Chandraprabha Vati
5. Telo-Extension
6. Moringa Capsules
7. Vrihat Vatchintamani Ras

Product Description

1. Boswellia Curcumin

Boswellia Curcumin capsules, a product of Planet Ayurveda, are enriched with goodness of the herbs shallaki (Boswellia serrata) and haridra (Curcuma longa). Both the herbs possess analgesic, antipyretic and anti-inflammatory properties. Boswellia Curcumin reduces the pain and other symptoms associated with amyloid polyneuropathy disease and also helps in the de-amyloidifying process of the involved nerves. Therefore, Boswellia Curcumin is beneficial in the condition of amyloid polyneuropathy disease. This product of Planet Ayurveda is a gem in the condition of diseased nerves and effectively manages amyloid polyneuropathy disease and brings back normal functioning of nerves.

Dosage: Two capsules twice a day with warm water after meals.

2. Neurogenie Capsules

Neurogenie capsules is a product of Planet Ayurveda which is composed of the herbs which are regarded as medhya in Ayurvedic texts and promote and improve neurological functions. The formulation contains the herbs brahmi (Bacopa monnieri) and ashwagandha (Withania somnifera). These are useful in promoting wellness of the nerves and coping up with neurological pain and numbness. And also helps in channelizing the mind in a positive direction and elevates the mood. With its nervine tonic actions, Neurogenie capsules are helpful in amyloid polyneuropathy disease.

Dosage: One capsule twice a day.

3. Ekangvir Rasa

Ekangvir Rasa is a classical herbomineral ayurvedic medicine that is much beneficial in vata disorders and neurological disorders such as paralysis, facial palsy, cervical spondylosis, brachial neuralgia etc. Ekangvir rasa contains purified mercury, purified sulphur, calx of manganese, pippali (Piper longum), shigru (Moringa oleifera), nirgundi (Vitex negundo), datura (Datura metel), triphala, chitrak (Plumbago zeylanica) etc. With its vata pacifying property, it is helpful in amyloid polyneuropathy disease.

Dosage: One tablet twice a day.

4. Chandraprabha Vati

Chandraprabha Vati is a classical formulation which is also known as Sarvaroga Pranashini which means it is used in all diseases/ailments. It pacifies all the three doshas. It contains a number of herbs and minerals. It is made up of daru haridra (Berberis aristata), sarjikakshara (Sodium carbonate), saindhava lavana (Rock salt), maricha (Piper nigrum), trivrit (Operculina turpethum), gaja pippali (Piper chaba), chitraka bark (Plumbago zeylanica), vanshlochan (Bambusa arundinacea), ela (Elettaria cardamomum) etc. Chandraprabha vati is used adversely in various health conditions related to the reproductive health of both men and women. Chandraprabha vati provides strength to the nerves and muscles. With its tridosha balancing properties it is helpful in Amyloid Polyneuropathy disease.

Dosage: Two tablets twice a day after meals with plain water.

5. Telo-Extension

Telo-extension is a formulation prepared by Planet Ayurveda which helps in hereditary conditions. The herbs in the formulation are ashwagandha (Withania somnifera), draksha (Vitis vinifera), amla (Emblica officinale), moringa (Moringa oleifera), pine bark (Pinus longifolia), giloy (Tinospora cordifolia) and rose hip (Rosa indica). All the herbs pacify the vata dosha. By targeting the telomere it helps in protecting the genome information and thus helps in various genetic or hereditary conditions. As amyloid polyneuropathy disease is a hereditary condition as well thus it helps in managing the same and also prevent further transferring the abnormal genetic information to the offsprings.And it also justifies the concept of beej dushti that is linked with this condition.

Dosage: One capsule twice a day.

6. Moringa Capsules

Moringa capsules, a product of Planet Ayurveda, are filled with extract of shobhanjan (Moringa oleifera). Moringa is such a beautiful herb that pacifies vata dosha and also helps in the spastitic condition of the muscles. It also promotes good coordination of the muscles. It is beneficial in neurological conditions due to its vata pacifying properties. Therefore, it helps in amyloid polyneuropathy disease.

Dosage: One capsule twice a day.

7. Vrihat Vatchintamani Ras

Vrihat Vatchintamani Ras is a classical Ayurvedic mineral formulation. The formulation’s ingredients are Rajata Bhasma (silver calx), Loha Bhasma (iron ash), Swarna Bhasma (gold calx), Abhrak Bhasma (mica ash), Pravala Bhasma (coral calcium), Mukta Bhasma (pearl calx) and Suta Bhasma (compound of purified mercury and purified sulphur). It also contains the benefits of Aloe vera. It is beneficial in demyelination conditions of nerves. It is useful in neurological diseases. It alleviates neurological pain. And helps in the delayed reflexes and also benefits in the condition of muscle spasms. As the name of the formulation suggests it magnificently pacifies the vitiated vata dosha condition. With these wonderful actions, Vrihat Vatchintamani Ras is a tremendous formulation in managing amyloid polyneuropathy disease.

Dosage: One tablet twice a day to be chewed.

Contact Planet Ayurveda Support Team to provide you the costing / ordering and delivery information at – costing.planetayurveda@gmail.com or Call at 0172-521-4040 (India), +91-172-521-4040 (Outside India) or Whatsapp at (+91) 9915-593-604

Conclusion

Amyloid polyneuropathy disease is an extremely troublesome condition. Amyloid neuropathy occurs due to deposition of amyloid protein in the nerves and is manifested by numbness, tingling or unusual sensation, pain in the nerve path involved. Further this can lead to loss of bladder and bowel control. It can also lead to shooting pain and sometimes it may result in loss of sensation and movement of a particular part according to the nerve involved. As there is no perfect management available for the condition of amyloid polyneuropathy disease in the contemporary system of medicines. And the stem cell transplant is an expensive procedure. But in the traditional system of Ayurvedic medicine, the management is based on the pacification of the vitiated doshas. In this condition, management is based on the pacification of the vata dosha and ama pachan. Above mentioned classical and formulations of Planet Ayurveda effectively manages the amyloid polyneuropathy disease with strengthening the nerves, removing the ama (endotoxins), and pacifying the vitiated kapha and vata dosha. Choose Ayurveda to Stay healthy and happy.